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Singapore


Fast Facts

  • Capital: Singapore
  • Economy: National economy is 39 largest in the world, nominal GDP US$ $308 billion 2014
  • Health Expenditure: 4.6 % of GDP, 2013
  • Population: 5.54 million, 2013
  • Average Life Span: 80.5.2 /84.9 (m/f), 2014 Rank 3rd in the world for life expectancy in 2015 with an average of 84.68 years
  • Languages: Malay, Chinese, English, Tamil
  • Adult Literacy Rate: 96.7% 2014

Health Trends

  • The WHO has ranked Singapore’s healthcare system as the best in Asia and sixth best in the world
  • Well-established healthcare system comprises a total of 13 private hospitals, 10 public (government) hospitals and several specialist clinics, each specializing in and catering to different patient needs, at varying costs. 
  • Shift of leading cause of death to non-communicable diseases. 
  • Effective implementation of childhood immunization program versus vaccine-preventable disease has contributed significantly to the reduction of the incidence of these diseases. 
  • Leading causes of death: Cancer, Ischaemic Heart Disease, Pneumonia, Cerebrovascular Disease, hypertensive diseases (including hypertensive heart disease), Other heart diseases, Diabetes mellitus, Chronic obstructive lung disease, Urinary tract infections, Nephritis, nephrotic syndrome and nephrosis.

Clinical Trial Landscape

  • Implemented the Singapore Guideline for Good Clinical Practice (SGGCP) on 1 Aug 1998, which was adapted from the International Conference on Harmonisation (ICH) Guideline for Good Clinical Practice (GCP) allowing clinical trials to be run ethically and setting scientific standards. This also provides the affirmation that results collected from clinical trials are reliable.
  • All clinical trials on investigational drugs that are conducted in Singapore require Clinical Trial Certificates (CTC) from the Health Products Regulation Group (HPRG), Health Sciences Authority.
  • Singapore plays a significant part in developing GCP in Asia as the secretariat for the APEC Coordinating Centre for Good Clinical Practice (GCP)
  • GCP inspection from the Regulatory Authority, Health Science Authority (HSA) was implemented in 2009 
  • Parallel submission to IRB and HA. 
  • Clinical trials setup timeframe approx 9-12 weeks. 
  • Singapore often achieves first site initiated or first patient included due to shorter start up timeframes. 
  • Most investigators are ICH-GCP trained. 
  • Majority of institutions have clinical trial centres which can assist in the set-up, conduct and coordination of clinical trials.

ICON in Singapore

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  • Presence in Singapore since 1999. 10th year celebrated this year
  • Central Laboratories established in June 2007 and 8,000 square foot facility opened in 2009.
  • Project management, study start-up and clinical monitoring experience in most therapeutic areas and indications

Services Offered

  • Project Management
  • Clinical Monitoring
  • Study start-up Services
  • Medical & Safety Services
  • Quality Assurance
  • Training
  • Central Laboratory Services:
    • Extensive test menu of safety, esoteric and custom-developed assays
    • Flow cytometry, molecular diagnostics and biomarker development
    • Sample tracking and storage
    • Fully CAP accredited
    • Comprehensive logistics support
    • Medically knowledgeable, on demand language interpretation service to assist sites
  • DOCS Resourcing Solutions:
    • Functional Resourcing
    • Flexible Resourcing
    • Permanent Recruitment


 

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