Advanced Features of NONMEM 7 Workshop

1st June, 2015
Time: 07:30 - 18:00

Advanced Features of NONMEM 7 Workshop

Location: Creta Maris Hotel - Hersonissos, Crete, Greece
Timezone: (GMT +1:00 hour) Brussels, Copenhagen, Madrid, Paris

A one-day NONMEM 7 course will be presented by ICON on Monday, 1 June 2015 at the Convention in Hersonissos, Crete, Greece

This workshop will cover the description and use of features in NONMEM 7. Workshop attendees will be instructed how to specify gradient precision for the improved FOCE algorithm, and will also be instructed on how to use the Monte Carlo importance sampling, stochastic approximation expectation-maximization methods, and full Bayesian methods. Parallel computing and dynamic memory allocation for efficient memory usage will also be described as well as new features of NONMEM 7.3, such as symbolic references to thetas, etas, and sigmas, priors to sigmas, MonteCarlo search algorithms to improve FOCE estimation, built-in individual weighted residuals, bootstrap tools for simulation, and greater control in average eta shrinkage calculations.

Also, using new abbreviated code features for easier modeling of inter-occasion variability, modeling additional mixed effects levels for grouping individuals, such as inter-clinical site variability, and using the new DO loop feature in abbreviated code, useful for handling multiple bolus doses in models that use the analytical absorption function for multiple transit compartments. The features of PDx-POP 5.1, the graphical interface for NONMEM 7, will also be demonstrated.

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