Interactive Response Technology

Clinical trial protocols are becoming more complex as clients seek to achieve multiple objectives with a single protocol.  This along with the demand for near time real-time critical data to support study decision making, has meant that the management of clinical supplies continues to be a cause for budget creep and potential delays. 

Interactive Response Technology (IRT) systems can assist with solving these challenges. They effectively manage patient enrolment, randomisation, dosing, clinical supplies, data integrations, drug returns, and drug reconciliation.

Innovative solutions from an expert team
We provide innovative solutions to support you in the proactive management of sites, patients, and clinical supplies. 

Experienced project management 
You will be partnered by a project manager who will be your main point of contact for the lifetime of you study.  They will identify the optimal solutions and governance models to meet the protocol and stakeholder objectives. Our project managemet team have a minimum of 6 years experience.  

Applied Innovation
FLEX ADVANTAGE is an IRT platform, offering enhanced randomisation and clinical supply management. It empowers study teams with a full complement of real time web reports available via a robust dashboard. The ad hoc reporting capability enables users to easily create custom reports and drill down functionality for better interaction and analysis of study data.

Seamless data integration
FLEX ADVANTAGE can be integrated with ICON technology solutions such as ADDPLAN, FIRECREST, ICONIK, Medical Imaging and external EDC, drug distributor and drug supply forecasting systems, providing study teams with complete visibility of the clinical supply chain, from distributor to patients.   

Robust System Development Life Cycle (SDLC)
Our SDLC has successfully passed regulatory, sponsor, and internal audits. Control points during each phase ensures the delivery of a quality system.

24 Hour Help Desk support
The ICON IRT Help Desk is available 24 hours a day, 7 days a week via email or phone. We support over 140 languages, and more than 90% of calls are handled on the first call.

Patient centric services

  • Management of patient enrolment to prevent over recruitment
  • Randomisation and treatment schemes to assign the right treatment at the right time to the right patient
  • Manage assignment of treatments and complex dose titrations to patients

Trial management and support

  • Clinical supplies management – automated site and depot medication inventory control, including expiry date management and drug recall
  • Coordination of forecasting vendors and other ICON services to improve the speed of data analysis for key trial milestones
  • Full adaptive trial support

In depth knowledge of trials and systems
We specialise in the design, development, validation, and management of Interactive Web Response systems (IWRS) for Phase I-IV clinical trials. We have over 17 years of experience in IRT and expertise ranging from small studies to large multinational project.

The study teams at ICON have vast understanding of the technical and clinical elements of IRT systems. This equips them to focus on building and managing a trial system according to your unique study requirements.

  • 1800+ studies implemented worldwide with 300+ current active studies   
  • Extensive experience in over 28 therapeutic areas
  • Management of over 50,000 sites in 85 countries, and over 25 million patient transactions 
  • Adaptive randomisation 75+ and Adaptive Trial Design 15 studies
  • Customer satiisfaction - reflected by 80% repeat business