X-Ray Powder Diffraction

X-Ray Powder Diffraction is a unique method for analyzing the basic structural properties of crystalline and semi-crystalline materials.

Powder diffraction patterns are characteristic of the spatial relationship of molecules in a crystalline lattice and can be used to identify the components of a material or to correlate its physical properties to solubility, strength, or appearance.

X-Ray Powder Diffraction plays an integral role in quality control, and research and development programs. Materials such as pharmaceuticals, ceramics, minerals, metals, alloys, inorganic and organic chemicals, and corrosion products may be analyzed quickly and cost effectively.

Applications Include:

• Polymorph Discrimination
• Qualitative Phase Identification
• Quantitative Determination
• Amorphous/Crystalline Characterization
• Impurity Analysis
• Phase Transformation Study

Qualitatitive identification of single- or multi-component crystalline samples is made by comparison to USP reference standards, NIST (NBS) standards, or other reference materials provided by our clients.

Differential Scanning Calorimetry (DSC) Analysis
DSC is a thermal analysis technique used to measure changes in heat flow associated with material transitions. It is commonly used to determine the glass transition temperature, crystalline melt point, and Heat Capacity. With our new TA Instruments MDSC Q2000 we can perform DSC and Modulated DSC analysis for your pharmaceutical testing needs. The DSC can be used in conjunction with our X-Ray Powder Diffraction services for the characterization of polymorphic transitions in your pharmaceutical products.