Comparing health care interventions and evaluating outcomes in real-world clinical practice

The comparison can be among multiple therapies, such as two competing medications, comparison of a medical versus a surgical intervention, or an evaluation of how new therapies are introduced and used in community practices. Overall, CER is applicable to evaluation of competing therapies, health care practices, clinical guidelines and behaviour modification.  

Study designs used for randomised clinical trials have been developed to asses therapies under ideal conditions, and may not be appropriate for CER, which must evaluate an array of real-world interventions and outcomes for patients with diverse characteristics.

ICON is experienced in the many approaches for designing and executing these studies, including:

  • Pragmatic Randomised Trials
  • Retrospective Studies
  • Disease Registries
  • Decision Models
  • Systematic Literature Reviews
  • Health Technology Assessments.