Clinical & scientific operations case studies

Maximising patient recruitment and retention, and expanding access to diverse patient populations.

We work with you to develop strategic, flexible approaches that leverage clinical informatics, state-of-the-art technologies, and our global reach to make data-driven decisions for every study.

From targeted engagement to global, multi-functional collaboration

In February 2023, a global biopharma company added ICON to its vendor ecosystem, initially focusing on Clinical Operations. Within a year, ICON grew to represent 20.5% of total FSP resourcing, outperforming expectations and becoming a key partner. ICON has since expanded into multiple services, offering flexible commercial models and scalable support across the client’s evolving needs.

Streamlining clinical operations

ICON successfully streamlined clinical operations during a post-market registry study by adapting sponsor SOPs mid-study, enabling a seamless transition to ICON-led project management while maintaining operational continuity and site performance.

Accelerating team growth to support client demand

This case study shows the effectiveness of this agile and forward-thinking approach to workforce scaling under time-
sensitive conditions.

Affiliate level solution

A mid-size pharmaceutical company with numerous affiliates and local vendors across 80 countries sought a reliable partner for effective Pharmacovigilance (PV) and Medical Information (MI) services.

Eliminating enrolment delays to bring an AI-enabled SaMD to market

A medical device developer faced clinical evaluation timeline delays due to under-enrolment. Discover how the collaborative partnership between the sponsor and ICON’s Medical Device & Diagnostics Research team steered the study from patient enrolment to FDA submission and approval.

Re-adjudicating a respiratory and cardiovascular trial during COVID-19

The FDA advised the trial to re-adjudicate so that the study accounted for the effects of COVID-19 on the trial outcomes. To ensure that the trial data would be submitted to the FDA as scheduled, ICON needed to coordinate re-adjudication of 700 endpoints within a compressed three-month timeline.

Automating EDC user access for improved trial efficiency

This case study demonstrates how ICON automated EDC user access management using API integrations and workflow automation, enhancing efficiency, security, compliance, and scalability in clinical trials while reducing costs and delays.

Overcoming activation and enrollment delays

ICON partnered with a drug development sponsor to conduct a global programme for Multiple sclerosis (MS) studies in over 2,200 patients.

Securing the CRA talent pipeline in the US for a pharmaceutical company

A multinational pharmaceutical company, of ICON’s functional services provider clients, approached our team to resource CRAs in the US.

Safety reporting continuity to protect patient safety and maintain compliance

Scientists are working diligently to learn more about the Coronavirus and health boards are changing guidance to adapt to
this newly available information.

Accelerating site proposal and selection

Timely patient recruitment is crucial to maintaining clinical trial timelines and budgets, but selecting the best and most engaged sites is challenging. Learn how ICON's proprietary One Search platform addresses this by aggregating and cleaning data from multiple sources.