ICON's cardiovascular trial experience, supported by a global team of experts
From genomics to the coming of age glycomics
Discover how glycan biomarkers are quickly becoming key elements of cancer, cardiovascular, and gastrointestinal research, setting the stage for a new golden age of epigenetic research and personalised therapeutics.
Mitigating the impact of COVID-19 on cardiovascular trials
COVID-19 has had a significant impact on the conduct of clinical trials and participants. Participants in cardiovascular (CV) trials typically are older, with underlying CV disease or risk factors such as hypertension and diabetes – a population at higher risk of death from COVID-19 if they contract the virus. As a result, these individuals may have heightened concerns about participating in a clinical trial due to the potential for exposure to COVID-19. Discover measures that can be implemented in ongoing trials to ensure the safety of participants, maximise retention and maintain trial integrity
Thriving in Value-Based Healthcare: A guide for cardiovascular medical device manufacturers
In December 2016, the Centers for Medicare & Medicaid Services (CMS) expanded the Bundled Payments for Care Improvement (BPCI) Initiative to include cardiovascular and hip fracture services, taking a major step in the march towards value-based care in the US. Read how can medical device manufacturers sustain growth and successfully navigate this new model?
Reimagining patient-centric clinical trials with the IoMT
Follow a theoretical patient through the entire clinical trial journey – from initial contact for an early study through transition to treatment with an approved product. At each stage, we explore how IoMT can increase clinical development programme efficiency by reducing the burden on patients, caregivers, pharma companies and medical device and diagnostic manufacturers.
Cardiovascular event adjudication during COVID-19 and beyond
In this webinar you will learn more about best practices for cardiovascular event adjudication across drug and device trials, including recent advances in the selection and application of connected devices.
Blogs and media articles relating to cardiovascular and metabolic clinical trials
Blog: Realising the benefits of bringing decentralised cardiovascular trials to patients
This blog reflects on the success of the first fully decentralised cardiovascular trial during the COVID-19 pandemic and highlights key elements for future trials.
Media article: Glycomics applications reinforce precision medicine
Nicole A. Cowan explores how glycomics is joining genomics and proteomics in the study of disease mechanisms and the development of novel therapeutics.
Blog: Data disruption: Navigating cardiovascular clinical trial adjudication during a respiratory pandemic
The COVID-19 pandemic disrupted clinical trials across all indications. For trials that persevered, COVID-19 impacted patient enrollment, participation, and data collection.
Media article: Ensuring Patient Safety and Cardiovascular Clinical Trial Integrity during a Global Pandemic
ICON experts share insights on ensuring patient safety and cardiovascular clinical trial integrity during the COVID-19 pandemic.
Blog: Managing trial participants with cardiovascular and metabolic disease during COVID-19
ICON recognises that the COVID-19 pandemic will have an impact on the conduct of ongoing and newly initiating clinical trials.
Media article: Mitigating the impact of COVID-19 on CV trials and participants
A thought leadership article authored by Jack Martin, Mary Jane Geiger and Deirdre Albertson which focuses on navigating cardiovascular clinical trials during COVID-19.
Blog: Digital health technologies - Implementing innovation in cardiovascular studies during COVID-19
ICON experts discuss how the COVID-19 pandemic has led to the implementation of more efficient cardiovascular (CV) trial designs and operational execution.
Media article: Adopting mHealth technologies in CV trials
The article discusses how, with the right approach and expert guidance, mHealth can help to collect new types of data and make trials more patient centric.
Blog: Reducing disruptions of cardiovascular trials and ensuring trial integrity during a global pandemic
Lessons learnt from Alzheimer’s trials could help in Parkinson’s drug development.
Blog: COVID-19, influenza and cardiovascular disease
Patients with cardiovascular disease are particularly susceptible to respiratory infections.
Cardiovascular clinical trials services at ICON
ICON has over 25 years' experience conducting cardiovascular trials, with particular emphasis on key cardiovascular/metabolic indications: heart failure, lipid disorders, diabetes, renal insufficiency and renal transplant, arrhythmia, and rare diseases.