Infectious Diseases
COVID-19 has raised the importance of research into fighting infectious diseases that threaten populations.
Antimicrobial resistance
The World Health Organization calls antimicrobial resistance, resulting from the overuse of antibiotics or other drugs, one of the top 10 public health threats. In fact, the next global pandemic could be another novel respiratory pathogen of zoonotic origins or a multidrug resistant strain of a previously eradicated pathogen.
In this whitepaper we provide a framework for understanding the antimicrobial crisis and the role healthcare and biopharma industries have to play in mitigating the impact of future pandemics.
Pre-register for the whitepaperThe evolution of HIV treatments
HIV is highly heterogeneous, creating barriers to diagnosing and treating the disease. Moreover, the HIV epidemic varies by region and country, necessitating different clinical research strategies across geographies. In this whitepaper, we discuss opportunities for addressing these challenges, best practices for managing infectious disease clinical trials and recent developments in HIV treatment.
Read the whitepaperPandemic respiratory vaccine clinical trials: A departure from business as usual
Vaccine trials for respiratory viruses, even in the best of circumstances, present a number of operational challenges for researchers, many of which are exacerbated in the face of a pandemic created by a novel virus. We focus on the corresponding success factors that can keep pandemic respiratory vaccine trials running at optimal speed and efficiency.
Read the whitepaperHIV infographic
HIV treatments: What has been achieved?
Before antiretroviral treatment availability, life expectancy for a person living with HIV was reduced by approximately 12.5 years. Now, this same individual will have near-normal life expectancy.
Download the infographicCoronavirus Observatory
The ICON Coronavirus Observatory applies powerful AI analysis and data visualisation to COVID-19 clinical trials news and social media, providing updates on the latest clinical trials, with insights into trending topics driving Coronavirus reporting. The Coronavirus Observatory also breaks down the global impact of the virus, looks at trending topics per country, and highlights important perspectives from the key organisations, including non-governmental organisations, public health authorities and the medical science community.
Download: Quick guide to the ICON Coronavirus Observatory (PDF)
Visit Coronavirus ObservatoryInfectious diseases and vaccines blogs
mRNA vaccines from COVID-19 to HIV
How one virus accelerated vaccine research, spurring innovation and hope for a cure in another.
COVID-19 vaccine trials
The success factors that can keep pandemic respiratory vaccine trials running at optimal speed and efficiency.
C diff and COVID-19
Is this a health risk that can be dealt with sooner than later?
Preparing for Disease X
A look at the potential impact of Coronavirus.
Post pandemic clinical trial strategies
How COVID-19 altered clinical trials forever and what’s next.
Diagnostics on the frontlines of COVID-19
Need for rapid diagnostic testing to identify and track people infected by or exposed to coronavirus.
Infectious diseases and vaccines media contributions
Inside the Pfizer/BioNTech COVID-19 vaccine trial: ‘We knew the world was watching and waiting for results’
An article featuring commentary from Dr. Nuala Murphy on ICON’s learnings from conducting the Pfizer/BioNTech trial.
Global collaboration: Irish company ICON on scaling up COVID-19 vaccine trials
An interview in which Steve Cutler gives a short overview of ICON and describes the company’s role in the Pfizer/BioNTech trial, explaining how the FDA played a critical role in expediting regulatory approvals.
The effect of Covid-19 solutions on the clinical trials process
Shelley McLendon, VP of Project Management, Vaccines and Infectious Diseases at ICON, outlines best practices that can keep trials running at optimal speed and efficiency, and the benefits of adopting a strategic partnership.
A challenge of pandemic proportions
ICON CEO Steve Cutler, discusses running the Pfizer / BioNTech vaccine trial, and how it proved the value of partnership, and the key role of technology.
What does it really take to conduct a vaccine trial at scale?
Dr Nuala Murphy, President of Clinical Services, talks exclusively to Pharmafield about the Pfizer / BioNTech COVID-19 vaccine trial and the implications this has on the future of drug development.
The current and future landscape of HIV treatments and vaccines
Dr. Caroline Forkin discusses the current status of HIV treatments and potential for researchers to develop a vaccine.
Rediscovering HIV: A new decade of research and innovation on the horizon
Dr. Caroline Forkin and Shelley McLendon discuss a new decade of research and innovation on the horizon for HIV.
Explore solutions to end AIDS epidemic
Running HIV trials requires new and creative approaches, to combat stigma and reflect the diverse cultural, lifestyle and biological circumstances.
Vaccine trials were run to the highest regulatory standards
COVID-19 vaccine trials.
Pfizer COVID vaccine trial proved remote monitoring, other innovations work
Starting clinical trials in weeks, as opposed to months, should be possible post-pandemic. (PDF)
Irish pharma group ICON carried out trial of Pfizer-BioNTech vaccine
Irish clinical trials group Icon has revealed that it carried out the late-stage trial of the Pfizer-BioNTech coronavirus vaccine.
Inside a vaccine trial
Dr. Murphy of ICON, provider of clinical services to Pfizer/BioNTech’s COVID vaccine program, discusses what it takes to conduct a vaccine trial of this scale.
Treatment options for Clostridioides difficile
An immediate by-product of the COVID-19 pandemic has been an increase in antimicrobialresistant infections, including Clostridioides difficile.
Here’s what we have to do to show a coronavirus vaccine works
The global effort to create a vaccine on such short notice is unprecedented.
ICON executives discuss key challenges of delivering a coronavirus vaccine
ICON mobilised its vaccine resources to address the COVID-19 global pandemic. (PDF)
The impact of influenza vaccination on the COVID-19 pandemic?
Evidence and lessons for public health policies.
Best practices in seasonal vaccine efficacy studies
Recommendations for study planning, enrolment, surveillance and study closeout.
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Receive new insightsInfectious diseases and vaccines services
ICON’s extensive Infectious Disease expertise enables us to consistently select the best sites, expedite start-up timelines, and achieve enrolment targets for our clients. We apply proven strategies to clinical trials that minimise risk and generate high-quality, reliable data reducing the time and cost of bringing new therapies to market.
Read more about ICON's services in infectious diseases and vaccines