Clinical & scientific operations case studies

Maximising patient recruitment and retention, and expanding access to diverse patient populations.

We work with you to develop strategic, flexible approaches that leverage clinical informatics, state-of-the-art technologies, and our global reach to make data-driven decisions for every study.

Accelerating study start-up through standardised IRT Integration

This case study highlights how a large sponsor reduced integration development time by 80%, accelerating study
start-up and cutting costs through the standardisation of IRT integration across programmes.

Strategic expansion of Clinical Operations support and TMF hub

In July 2024, a global biopharma client partnered with ICON to expand functional support. Starting with Clinical Operations and TMF roles, the partnership grew to over 60 FTEs and now includes Clinical Quality, Systems Experts, and Late Phase, with further expansion underway.

From targeted engagement to global, multi-functional collaboration

In February 2023, a global biopharma company added ICON to its vendor ecosystem, initially focusing on Clinical Operations. Within a year, ICON grew to represent 20.5% of total FSP resourcing, outperforming expectations and becoming a key partner. ICON has since expanded into multiple services, offering flexible commercial models and scalable support across the client’s evolving needs.

Streamlining clinical operations

ICON successfully streamlined clinical operations during a post-market registry study by adapting sponsor SOPs mid-study, enabling a seamless transition to ICON-led project management while maintaining operational continuity and site performance.

Accelerating team growth to support client demand

This case study shows the effectiveness of this agile and forward-thinking approach to workforce scaling under time-
sensitive conditions.

Enabling privacy-safe, high-performing digital campaign targeting

Symphony Health, part of ICON plc, partnered with Butler/Till to boost a pharma client’s digital media strategy. Using advanced data and targeting, they improved reach and cut costs per diagnosed patient.

Affiliate level solution

A mid-size pharmaceutical company with numerous affiliates and local vendors across 80 countries sought a reliable partner for effective Pharmacovigilance (PV) and Medical Information (MI) services.

Eliminating enrolment delays to bring an AI-enabled SaMD to market

A medical device developer faced clinical evaluation timeline delays due to under-enrolment. Discover how the collaborative partnership between the sponsor and ICON’s Medical Device & Diagnostics Research team steered the study from patient enrolment to FDA submission and approval.

Re-adjudicating a respiratory and cardiovascular trial during COVID-19

The FDA advised the trial to re-adjudicate so that the study accounted for the effects of COVID-19 on the trial outcomes. To ensure that the trial data would be submitted to the FDA as scheduled, ICON needed to coordinate re-adjudication of 700 endpoints within a compressed three-month timeline.