Clinical & scientific operations case studies

In July 2024, a global biopharma client partnered with ICON to expand functional support. Starting with Clinical Operations and TMF roles, the partnership grew to over 60 FTEs and now includes Clinical Quality, Systems Experts, and Late Phase, with further expansion underway.

ICON successfully streamlined clinical operations during a post-market registry study by adapting sponsor SOPs mid-study, enabling a seamless transition to ICON-led project management while maintaining operational continuity and site performance.

Symphony Health, part of ICON plc, partnered with Butler/Till to boost a pharma client’s digital media strategy. Using advanced data and targeting, they improved reach and cut costs per diagnosed patient.

A mid-size pharmaceutical company with numerous affiliates and local vendors across 80 countries sought a reliable partner for effective Pharmacovigilance (PV) and Medical Information (MI) services.

A medical device developer faced clinical evaluation timeline delays due to under-enrolment. Discover how the collaborative partnership between the sponsor and ICON’s Medical Device & Diagnostics Research team steered the study from patient enrolment to FDA submission and approval.

The FDA advised the trial to re-adjudicate so that the study accounted for the effects of COVID-19 on the trial outcomes. To ensure that the trial data would be submitted to the FDA as scheduled, ICON needed to coordinate re-adjudication of 700 endpoints within a compressed three-month timeline.

This case study demonstrates how ICON automated EDC user access management using API integrations and workflow automation, enhancing efficiency, security, compliance, and scalability in clinical trials while reducing costs and delays.

ICON partnered with a drug development sponsor to conduct a global programme for Multiple sclerosis (MS) studies in over 2,200 patients.

Scientists are working diligently to learn more about the Coronavirus and health boards are changing guidance to adapt to
this newly available information.

Timely patient recruitment is crucial to maintaining clinical trial timelines and budgets, but selecting the best and most engaged sites is challenging. Learn how ICON's proprietary One Search platform addresses this by aggregating and cleaning data from multiple sources.

ICON's Safety Reporting Solution ensured regulatory compliance during global trials by adapting to pandemic-related disruptions.

ICON was tasked with providing a rapid and flexible IRT solution for a multinational infectious disease vaccine trial with over 30,000 subjects in 100+ locations.