Infectious Diseases
COVID-19 has raised the importance of research into fighting infectious diseases that threaten populations.
COVID-19 vaccines: Post-authorisation safety surveillance
This whitepaper explores the multifaceted challenges of COVID-19 post-authorisation safety surveillance studies and how business intelligence tools can benefit these efforts.
Assessing strategies for mitigating infectious diseases
Public health officials turn to evidence as the basis for their health policies to control the spread of infections. However, many nuanced factors can influence variations in the number of infections caused by a single infected individual.
Watch the webinar: An introduction to infectious disease modelling
In this whitepaper, we explain the basic measures used to quantify infectious disease transmission and introduce the principles of dynamic modelling to inform the selection of the most effective and cost-efficient strategies for mitigating infectious diseases.
Fortifying vaccines: Preparation and prevention against future infectious disease epidemics
This whitepaper presents infrastructural and strategic considerations for strengthening vaccine development so that the medical community will be prepared to respond to future pandemics and novel diseases.
Antimicrobial resistance
The World Health Organization calls antimicrobial resistance, resulting from the overuse of antibiotics or other drugs, one of the top 10 public health threats. In fact, the next global pandemic could be another novel respiratory pathogen of zoonotic origins or a multidrug resistant strain of a previously eradicated pathogen.
In this whitepaper we provide a framework for understanding the antimicrobial crisis and the role healthcare and biopharma industries have to play in mitigating the impact of future pandemics.
The evolution of HIV treatments
HIV is highly heterogeneous, creating barriers to diagnosing and treating the disease. Moreover, the HIV epidemic varies by region and country, necessitating different clinical research strategies across geographies. In this whitepaper, we discuss opportunities for addressing these challenges, best practices for managing infectious disease clinical trials and recent developments in HIV treatment.
Pandemic respiratory vaccine clinical trials: A departure from business as usual
Vaccine trials for respiratory viruses, even in the best of circumstances, present a number of operational challenges for researchers, many of which are exacerbated in the face of a pandemic created by a novel virus. We focus on the corresponding success factors that can keep pandemic respiratory vaccine trials running at optimal speed and efficiency.
HIV infographic
HIV treatments: What has been achieved?
Before antiretroviral treatment availability, life expectancy for a person living with HIV was reduced by approximately 12.5 years. Now, this same individual will have near-normal life expectancy.
Infectious diseases and vaccines blogs
Beyond tradition: An analysis of modern vaccine technologies
This blog explores some of the most promising non-viral vaccine development platforms, highlighting their mechanisms, advantages, and limitations.
Why long-term follow-up should start early in vaccine trials
Learn more about why demonstrating long-term safety should start early in vaccine trials. With early planning, vaccine developers can gather real-world data and evidence needed to help individuals make informed decisions about vaccination.
Technology and tokenisation: Reflections from the 2025 World Vaccine Congress
Dive into the main themes, topics and outlooks from the 2025 WVC, held in Washington, D.C., where ICON presented and was recognised at the ViE Awards.
The race to develop combination vaccines – and the importance of indirect effects
A development race is currently underway in the field of combination vaccines, with a number of influential pharmaceutical and biotech companies pursuing combination vaccines targeting influenza and COVID-19.
Disease surveillance in low- and middle-income countries
Disease surveillance and reporting is critical to public health, enabling faster and better response to infectious disease outbreaks.
Disease surveillance and innovative vaccines
Learn about current approaches to disease surveillance and why they are important for the advancement of vaccine development in this blog.
Pre-emptive vaccine research to improve EID response
This blog explores strategies for strengthening vaccine development so that the medical community is better prepared to respond to future epidemics.
From clinician visits to data analysis: the challenges and solutions in COVID vaccine pharmacovigilance
Learn more about the challenges and solutions in assessing the long-term effects of Covid and Covid vaccines in this blog.
Infectious diseases and vaccines media contributions
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Media article: While the world waits
ICON's Cindy Dukes considers the best practices for developing a vaccine and treatments for COVID-19.
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Media article: Coronavirus vaccine: how pharma is picking up the pace
A PharmaPhorum article featuring commentary from ICON's Dr. Nuala Murphy and Dr. James Cummings.
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Media article: COVID-19 will spur decentralised and hybrid trials – Novartis hails digital investment
An article featuring commentary from Dr. Nuala Murphy regarding the use of decentralised and hybrid trials during the COVID-19 crisis.
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Media article: COVID-19 vaccine response
James Cummings, President, ICON Government & Public Health Solutions, and Beth Tulip, Vice President, Project Management, Vaccines & Infectious Diseases, discuss developments in vaccine research efforts and key challenges of delivering a coronavirus vaccine.
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Media article: ICON launches Coronavirus Observatory
This article discusses ICON’s Coronavirus Observatory, a tool providing real-time updates on COVID-19 vaccine trials, and insights into key issues.
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Media article: Best Practices in Seasonal Vaccine Efficacy Studies: Tips for Successful Planning and Execution
Recommendations for study planning, enrolment, surveillance and study closeout.
Receive more insights on infectious diseases and vaccines from ICON
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Infectious diseases and vaccines services
ICON’s extensive Infectious Disease expertise enables us to consistently select the best sites, expedite start-up timelines, and achieve enrolment targets for our clients. We apply proven strategies to clinical trials that minimise risk and generate high-quality, reliable data reducing the time and cost of bringing new therapies to market.