The growing demand for real world evidence

Decision makers today demand evidence that reflects real clinical practice and meets rising regulatory and payer expectations. ICON Real World Solutions delivers scientifically rigorous real world evidence (RWE) to support development, authorisation and commercial success.

We bring together global operations, advanced data technologies and deep epidemiological expertise in a single, integrated real world evidence ecosystem.

Evidence across the development lifecycle

Our evidence generation progresses in depth and impact from early proof of concept through phase 4 and post-approval commitments. From pragmatic trials and registries to large scale database analyses and external control arms, we design evidence strategies that evolve with your asset.

Global delivery at scale

  • 750+

    Real world studies spanning 20+ therapeutic areas
  • 259,000+

    Patients
  • 36,100+

    Sites worldwide
  • 950+

    RWE project managers, epidemiologists, health economists, biostasticians, medical writers, and data scientists

An integrated real world evidence model

ICON uniquely combines scientific leadership, global execution and advanced data technologies into a single, cohesive RWE platform using a layered evidence strategy.

RWE

Primary data from registries, non-interventional studies, pragmatic trials and extension studies

RWE

Secondary data from claims, electronic health records, disease registries and social determinants of health

RWE

Complementary sources including patient reported outcomes, surveys, wearables and laboratory data

RWE

Advanced analytics powered by AI and machine learning

Why sponsors choose ICON to build evidence that matters

Evidence designed for regulatory & payer alignment

Dedicated global team with deep real world research expertise

Scientifically robust & defensible methodologies

Improved patient experience & reduced site burden

Case studies

See our real world solutions in action through case studies spanning diverse study designs and therapeutic areas, supported by deep scientific expertise.

Learn more