All case studies

Highlights

We focus our innovation on the factors that matter most — accelerating time to market, reducing costs and enhancing quality. Learn more about how we've helped clients meet and exceed their goals in this selected library of case studies.

Proactive patient retention strategy in a GLP-1 RA trial

Explore how ICON successfully supported a sponsor’s cardiovascular outcome trial for a GLP-1 receptor agonist with 9,900+ patients with type 2 diabetes and maintained a retention rate of 97% over 7 years.

A small biotech success story

A small US-based biotech company was in a race to be the first to market with their lead targeted oncology product.

FSP partnership - sustained efficiency and ongoing innovation

The implementation of an FSP model across our partner's project management function, led to 20% cost efficiences and a 30% reduction in client burden.

By taking a site and patient-centric approach, and leveraging advanced tools and real-time data insights, we maximise patient access, recruitment, and retention—ensuring that every trial is conducted with efficiency, agility, and a commitment to improving patient outcomes.

All case studies

Filter our case studies by categories, selecting amongst our broad range of solutions.

Automated conversion and load, including manual enrichment

ICON was asked to support a client with migrating data from an existing Regulatory Information Management (RIM) system into a new system. During migration, the ICON team needed to ensure the safety reporting requirements were correctly described in the new system as current data were incorrect and/or incomplete.

Regulatory project management scenario planning (Oncology)

ICON was asked to provide scenario planning related to accelerating the marketing authorisation application (MAA) approval through various clock-stop scenarios.

EDMS (Electronic Document Management System) expanded to a newly acquired business unit

Following a corporate acquisition, the ICON Regulatory Technology & Information Management (RTIM) team was engaged by a mid-sized life sciences company to re-design, configure, and deploy the existing EDMS to a new business unit.

XEVMPD/SPOR Compliance

The European Medicines Agency (EMA) is in the process of implementing IDMP standards that specify standardized definitions to identify and describe medicinal products for human use only.

Regulatory Guidance for Established Products

A top-10, multinational pharmaceutical company needed to enhance product support and improve its in-house development.

Investigational New Drug (IND) Application

A small company, with limited internal resources, was planning to submit two new INDs and reached out to ICON to help manage the IND filings.

Clinical trial with combination product and medical devices

ICON provided regulatory support for a study to develop a novel treatment for patients using an implantable combination product and three separate medical devices.

Combined study with in vitro device investigating an oncology treatment

A study sponsor was investigating a biological treatment for oncology patients in addition to the standard of care chemotherapy. They sought regulatory support from ICON due to the study’s complexity, the geographic span and because the IVD was used out of its intended purpose.

Proactive patient retention strategy in a GLP-1 RA trial

IRT User Acceptance Testing

Resolving critical issues and ensuring trial integrity

Regulatory Strategy in Clinical Development (EU)

"A large pharma customer sought expert regulatory support from ICON for a paediatric rare disease development
program."

Increased compliance for complex Alzheimer’s disease study

The sponsor in this case was a large pharmaceutical company that contracted ICON to manage and streamline the training and compliance workload for their phase 2 Alzheimer’s study.

Solutions case studies

Our solutions span the entire lifecycle of product development and can be adapted to suit small local trials or large global programs. Explore our work in the different aspects of our solutions.

Let's collaborate

Discover how ICON's expertise transforms clinical trials.

Blogs

Stay informed with ICON's expert insights on clinical trials, regulatory changes, and industry trends. Our blogs provide practical advice, innovative solutions, and thought leadership from global experts.

News

Stay updated with our latest news on partnerships, financial results, technological advancements, and industry insights.

Insights

Explore ICON's expert analysis and practical advice on the latest operational, regulatory, technological and economic challenges in clinical research. Our insights provide thought leadership and innovative solutions to transform trials.

Case studies

Highlights

Proactive patient retention strategy in a GLP-1 RA trial

A small biotech success story

FSP partnership - sustained efficiency and ongoing innovation

All case studies

Automated conversion and load, including manual enrichment

Regulatory project management scenario planning (Oncology)

EDMS (Electronic Document Management System) expanded to a newly acquired business unit

XEVMPD/SPOR Compliance

Regulatory Guidance for Established Products

Investigational New Drug (IND) Application

Clinical trial with combination product and medical devices

Combined study with in vitro device investigating an oncology treatment

Proactive patient retention strategy in a GLP-1 RA trial

IRT User Acceptance Testing

Regulatory Strategy in Clinical Development (EU)

Increased compliance for complex Alzheimer’s disease study

Solutions case studies

Let's collaborate

Blogs

News

Insights