ICON’s extensive Infectious Disease expertise enables us to consistently select the best sites, expedite start-up timelines, and achieve enrolment targets for our clients. We apply proven strategies to clinical trials that minimize risk and generate high-quality, reliable data reducing the time and cost of bringing new therapies to market.
ICON Infectious Diseases experience
Infectious Diseases capabilities
ICON’s Infectious Disease team understands the urgency, complexities, and potential challenges associated with infectious diseases. Our experience inlcudes treating hospitalized patients with respiratory infections including COVID-19, severe influenza and pneumonia. This presents a great opportunity for ICON to make data-driven recommendations and apply best practices to execute your studies while safeguarding patients. By selecting ICON as your contract research organization (CRO) partner, you will benefit from:
- Leadership team focused specifically in Infectious Diseases with well over 200 years of combined experience in infectious diseases clinical development, who provide insight into your protocol and strategies to operationalize execution.
- Experience with 129 infectious disease treatment studies within the past five years alone, including 20 ongoing COVID-19 treatment studies.
- Over 40 studies conducted within the past 5 years investigating infectious disease treatments in hospitalized patients.
- Our global COVID-19 team, including medical and drug development experts, is scalable and ready to be deployed.
- Best practices and learnings from our ongoing COVID-19 treatment studies.
- Global Site Network (GSN) and Patient Solutions comprised of ICON’s proprietary and vaccine-experienced health care alliance (HCA) sites that are prepared to conduct COVID-19 treatment trials.
- Through FIRECREST digital solutions our learning and digital experts have considerable experience in developing engaging study focused content.
COVID-19 clinical operations
Keeping your clinical trial on track in an evolving environment.
Adapting operations to changing conditions
ICON has adapted its services to support sponsors during this time; offering remote monitoring where on-site visits were not permitted, providing additional support to get IMP to patients and pre-recording investigator meetings because of travel restrictions.
Treatment and vaccine trials for COVID-19
ICON is proud to be supporting clients and government organisations in the search for a treatment or vaccine for COVID-19. Download our whitepaper on Pandemic respiratory vaccine clinical trials.
Excellence in Microbiology (EIM) Committee
World Class team of experts with extensive microbiology experience that collaborate with scientists to ensure the most appropriate protocol design and best in class analytical methods. The committee also partners to ensure quality, timely and accurate results reporting.
Government sponsored & funded studies
For nearly 25 years, ICON has managed basic, applied, and clinical research operations for studies both sponsored, and funded by Government and Public Health bodies, including the United States (US) Government including the U.S. military, the National Institutes of Health (NIH), as well as commercial customers and academic institutions receiving federal research funding. We have supported basic, applied, and clinical infectious disease biomedical research efforts and several hundred clinical trials with over 7,000 subjects – many in the areas of vaccines, antivirals, antibiotics, and other treatments for infectious diseases. We provide concept identification, bench testing, biosafety Level- (BSL-) 3/4 testing, product manufacturing support, and clinical trials for bacterial, viral, parasitic, and emerging diseases.
ICON’s clinical research and laboratory services offer the optimal trial experience for clients and investigative sites by using an integrated approach to Infectious Disease study execution:
- Lab team members are fully integrated into study teams
- Culture, identification and susceptibility
- Customized minimum inhibitory concentrations (MIC)
- Testing all specimen types & Isolates
- Semi-quantitative and quantitative cultures
- Species level identification
- Anaerobic chambers for culture and susceptibility tests
- Long-term storage
- Custom assay transfer & validation