We provide end-to-end bioanalytical support from Pre-Clinical to Phase IV studies in state-of-the-art clinical facilities.

At ICON, our clinics are managed, staffed, and supported by industry-leading experts who have the scientific knowledge and experience to successfully deliver even the most complex of studies. We operate state-of-the-art facilities in the Netherlands and North America, as well as an innovative patient pharmacology model in Central and Eastern Europe. In addition, our laboratory facilities are situated close to our clinical facilities and configured to support all study requirements.

Clinical Research Unit: Lenexa, Kansas, USA

From First-in-Human to Proof-of-Concept programs, we can help take your product from concept to compound to cure.

Our strategically located, state-of-the-art clinical research center in Lenexa, Kansas has 114 patient beds and a GMP-practicing pharmacy. We can handle all types of formulations in our temperature- and humidity-controlled setting and our co-located bioanalytical laboratory ensures rapid sample processing for critical, dose-escalation, and decision-making involving pharmacokinetic assays. We have extensive experience in:

  • Focused First-in-Human studies through Proof-of-Concept
  • Vaccine studies

Clinical Research Unit: Salt Lake City, Utah, USA

We’re shaping the future of clinical research at our state-of-the-art Phase I Clinic in Salt Lake City, Utah.

Our 136-bed Salt Lake City clinic was custom-built for First-in-Human and early phase studies in healthy volunteers and patients. We are strategically located across the street from a trauma hospital and can fully support timely, efficient data collection while always ensuring the safety of each study participant. We also provide dedicated patient wards, private dosing rooms, and flexible space to accommodate your rigorous assessment needs.

Our meticulously designed investigative unit supports the precise execution of all early phase clinical trials. Although we’re capable of conducting studies across all therapeutic areas, we have a particular focus in CNS with neurology and psychiatry specialization, analgesia, abuse liability, and sleep medicine.

Clinical Research Unit: San Antonio, Texas, USA

The San Antonio Clinical Research Unit is a customized site capable of meeting the ever changing requirements for clinical trials.

The site’s facilities include 120 available beds with a private bath area in each room, ICU ward with 10 beds, pharmacy and drug storage, an on-site PK laboratory, clinical laboratory and a 48-channel Mortara ECG system.  Since 2008 the site has conducted more than 360 Phase I studies. Our experienced staff provides expert delivery of services to safely and efficiently manage early-phase studies from First-in-Human to proof of concept. This includes all services such as an active volunteer database, data collection fully aligned to FDA guidelines, electronic data capture and regulatory approvals. Clinical trial experience includes:

  • First in Human
  • Maximum Tolerated Dose Studies
  • SAD
  • MAD
  • Food Effects Pharmacokinetics / Pharmacodynamics Studies
  • Drug – Drug Interaction (DDI) Studies
  • Bioequivalence
  • Thorough QTc
  • Vaccine
  • Patient populations including diabetic, obese, elderly, postmenopausal, NASH and gastrointestinal disorders
  • Adaptive design
  • Device Studies
  • Biosimilars

San Antonio CRU
Main number: 210-283-4500
Recruitment: 210-225-5437 or 877-848-7425
Recruitment website: www.somethingtobeproudof.com

Clinical Research Unit: Budapest, Hungary

Providing accessible Phase I solutions throughout Hungary.

Our Budapest clinic focuses on oncological, ADME, and mass balance studies, as well as rheumatology and renal impairment studies. As one of only 14 accredited Phase I units in Hungary, our centrally located clinic is easily accessible to patients and is within close proximity of additional hospital services if required. We’ve also developed excellent working relationships with university clinics and top institutions throughout the region to ensure we provide the safest, most effective solutions.

Clinical Research Unit: Groningen, the Netherlands

From First-in-Human to Proof-of-Concept programs, we can help take your product from concept to compound to cure.

Our 150-bed Clinical Pharmacology Unit in Groningen, the Netherlands is strategically located and directly connected to the Martini Hospital, including direct access to their intensive care unit. This partnership ensures we have access to the latest tools, technology, and expertise. We have extensive experience in:

  • First-in-Human studies
  • Positron emission tomography (PET)
  • Functional magnetic resonance imaging (fMRI) scans
  • Cerebral spinal fluid (CSF) sampling
  • Validated pain models
  • Cognitive testing
  • Spirometry
  • ADME studies

Clinical Research Unit: UCMG (Academic hospital Groningen)

In early 2022 ICON entered into a partnership with the University Medical Center Groningen (UMCG), one of the largest academic hospitals in The Netherlands, renowned for performing cutting-edge scientific research. This unique collaboration resulted in the construction of a combined clinical research unit on the UMCG campus.

This joint unit holds 13 hospital based beds, enabling the execution of innovative study designs and clinical trials that incorporate particularly invasive or specialized assessments in healthy subjects, like continuous CSF sampling and various medical imaging techniques like (f)MRI, SPECT, CT and PET. In addition, the unit offers the opportunity to carry out early and late phase clinical research in special moderate to severe patients who have to stay in a hospital environment.

It has been designed in accordance with good clinical practice (GCP) to accommodate the delivery of complex clinical trials through all phases of research and is fully integrated with our GRQM unit, using ICON supported quality and IT systems. Take a tour of our new clinic below: