ADME
Radioactivity analysis for human ADME and radiokinetic studies
Fast, reliable data for your human ADME trials
ICON provides end-to-end services to ensure the successful and accelerated delivery of high-quality data for your human ADME studies. Our integrated approach helps you meet regulatory requirements while optimising timelines and budgets.
Rapid radiokinetic insights
With multiple LSC instruments on-site and deep expertise in sample processing—including feces homogenization and combustion—our isotope laboratory delivers total radioactivity results within 24 hours of sample collection. This enables:
- Fast calculation of excretion balance
- Quick verification of discharge criteria
- Reduced clinic stay for participants
- Lower overall trial costs
Enhanced safety & compliance
Our experienced medical staff and clinical pharmacologists perform precise dosimetry calculations to ensure full compliance with ICRP guidelines and the ALARA principle. This minimizes exposure to radiolabeled investigational products, enhancing participant safety and regulatory confidence.
Seamless microdose study support
For microdose designs, ICON partners with trusted vendors offering accelerated mass spectrometry (AMS) services. We manage the full process—from vendor coordination and sample processing to logistics and reporting—delivering streamlined operations, reliable AMS data and timely excretion balance calculations.
Contact us today
Explore how our solutions will ensure the successful and accelerated delivery of high-quality data for your human ADME studies, helping you to meet regulatory requirements while optimising timelines and budgets.
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