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ICON SWIM

Screening window intelligent management system: keeping every patient on track

In a MASH study, everyday counts. The 56-day screening window is a short timeline where participants must complete a complex series of assessments — labs, MRI, liver biopsy, DEXA, and more. Missing even one can mean screen failure, lost patients, and delayed timelines.

That’s why ICON developed SWIM, a screening window intelligent management system.
Accessible through Firecrest, ICON SWIM is a smart, automated tool that brings precision, visibility, and control to the entire screening process.

The challenge

The screening window is unforgiving. It defines the start of every MASH study and determines its success. Yet, many sites still rely on manual spreadsheets and individual tracking to manage dozens of overlapping deadlines.

Without real-time visibility, even one missed appointment or late test can cascade into lost patients and missed enrollment targets.

ICON SWIM changes that.

ICON SWIM automates and orchestrates the entire screening window.

From the moment a patient is screened, it:

  • Auto-populates deadlines for every required activity.
  • Highlights the optimal “sweet spot” for each test.
  • Issues early warnings when milestones are at risk.
  • Provides sponsors and sites with a shared, real-time view of progress.

No more guesswork. No more blind spots. Just clarity, precision, and confidence.

How it works

  • 1

    A patient is screened.

    ICON SWIM instantly calculates the full set of screening deadlines.

  • 2

    Tasks are scheduled.

    Sites see a clear timeline for each required procedure.

  • 3

    Notifications trigger automatically.

    Teams are alerted before deadlines approach or risk being missed.

  • 4

    Sponsors gain oversight.

    Real-time dashboards track progress across all sites, ensuring operational excellence.

All of this happens within Firecrest, creating a single, seamless experience for site users.

Empowering sites, building sponsor trust

  • for sites

    ICON SWIM brings control back to the forefront. No more manual tracking or second-guessing timelines — just clear direction and timely reminders.

  • for sponsors

    ICON SWIM demonstrates operational rigor. It shows every screening activity in motion, delivering measurable improvements in screening success rates, cycle times, and first patient in.

  • together

    ICON SWIM + Firecrest form a powerful ecosystem — empowering sites, assuring sponsors, and driving studies forward.

Why it matters

Because in MASH studies, the screening window is more than a deadline — it’s a promise.

  • A promise to patients that their time matters.
  • A promise to partners that every site is supported.
  • And a promise to sponsors that operational excellence underpins every step of the study.

With ICON SWIM, teams keep their promise - with precision, visibility and trust.

Key benefits at a glance:

For sites

  • Auto-calculated screening deadlines
  • Clear visual timeline and alerts
  • No more manual spreadsheets
  • Fully integrated in Firecrest

For sponsors

  • Real-time oversight of all screening activity
  • Reduced screen failure rates
  • Faster First Patient In (FPI)
  • Demonstrated operational excellence

For patients

  • Efficient, predictable scheduling
  • Fewer re-tests and visit delays
  • Confidence that their participation matters
  • Seamless study experience

Why ICON?

ICON combines deep operational experience with cutting-edge technology.
By integrating ICON SWIM into Firecrest, we’re not just tracking timelines — we’re transforming them into a foundation for success.

With a heritage of delivering precision at scale, ICON ensures that every study milestone is met, every window is protected, and every patient stays on track.

Ready to keep every patient on track?

Discover how ICON SWIM can reduce screen failures, accelerate First Patient In, and deliver the confidence your teams and patients deserve.

Request a demo
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